Hunting a “Jekyll-and-Hyde” molecule | MIT News

Cortez Deacetis

MIT chemical engineers have developed a way of swiftly screening compounds to determine their therapeutic potential for certain kinds of cancers. With a genetically engineered sensor and high-throughput technology, their method probes for changes in cellular concentrations of hydrogen peroxide (H2O2), a specialized molecule known as an oxidant. “The regulatory […]

A small molecule induces readthrough of cystic fibrosis CFTR nonsense mutations — ScienceDaily

Cortez Deacetis

An experimental drug documented in Mother nature Communications suggests that a “route is obviously achievable” to deal with currently untreatable conditions of cystic fibrosis ailment induced by nonsense mutations. This consists of about 11 p.c of cystic fibrosis patients, as perfectly as people with other genetic disorders, which includes Duchenne […]